Local and systemic cytokine profiles in children with pneumonia-associated lung consolidation
IL-4, INF-γ, IL-2R, and IL-8 levels in BALF are closely associated with pulmonary complications and disease progression in children with LC. Exploring targeted immunomodulatory therapies in these children may mitigate lung injury caused by excessive local inflammatory responses.
Authors
- Yong Yin (ORCID: https://orcid.org/0000-0001-8222-9316)
- Guijun Yang (ORCID: https://orcid.org/0000-0002-6425-8321)
- Mingyu Tang
- Jilei Lin (ORCID: https://orcid.org/0000-0003-1920-9317)
- Huishan Zhang (ORCID: https://orcid.org/0000-0001-5324-9959)
- Wanlin Li (ORCID: https://orcid.org/0000-0003-1975-2002)
- Jiande Chen (ORCID: https://orcid.org/0000-0001-7884-3460)
- Shuhua Yuan (ORCID: https://orcid.org/0009-0008-8212-7342)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-6871-307X)
- Hui Zhao (ORCID: https://orcid.org/0000-0003-0866-6037)
- Lei Zhang (ORCID: https://orcid.org/0000-0001-7769-7377)
Institutions
- Shanghai Children's Medical Center (CN)
- Linyi People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1546730
- Citations
- 2
- Primary Topic
- Pediatric health and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 5.03
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- Shanghai Jiao Tong University