Case Report: Phosphaturic mesenchymal tumor presenting solely as knee pain without hypophosphatemia

Phosphaturic mesenchymal tumor (PMT) is a rare tumor disease that often leads to tumor-induced osteomalacia (TIO). The typical manifestations of this disease include hypophosphatemia and osteomalacia. The main symptom in most PMT patients is diffuse pain throughout the body. However, we report a PMT patient with typical histological features but without hypophosphatemia and TIO. This patient only presented with pain in the right knee joint. At 6 months and 1 year after surgery, follow-up revealed that the patient's swelling and pain in the right knee joint had disappeared. Moreover, the imaging and biochemical examinations conducted at the local hospital showed normal results.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-05-08
DOI
https://doi.org/10.3389/fonc.2025.1597194
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Case Report: Phosphaturic mesenchymal tumor presenting solely as knee pain without hypophosphatemia

Zhipeng Dai, Qianqian Cao, Cheng Cheng
Frontiers in Oncology
Parathyroid Disorders and Treatments
article

Case Report: Phosphaturic mesenchymal tumor presenting solely as knee pain without hypophosphatemia

Zhipeng Dai, Qianqian Cao, Cheng Cheng
article en

Abstract

Phosphaturic mesenchymal tumor (PMT) is a rare tumor disease that often leads to tumor-induced osteomalacia (TIO). The typical manifestations of this disease include hypophosphatemia and osteomalacia. The main symptom in most PMT patients is diffuse pain throughout the body. However, we report a PMT patient with typical histological features but without hypophosphatemia and TIO. This patient only presented with pain in the right knee joint. At 6 months and 1 year after surgery, follow-up revealed that the patient's swelling and pain in the right knee joint had disappeared. Moreover, the imaging and biochemical examinations conducted at the local hospital showed normal results.

Frontiers in OncologyVol. 15
Zhengzhou University (CN), Henan Provincial People's Hospital (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 89%
Parathyroid Disorders and Treatments
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