Identification of biomarkers and immune microenvironment associated with heart failure through bioinformatics and machine learning
This study identifies <i>HMGN2</i>, <i>HTRA1</i>, <i>MFAP4</i>, and <i>MYH6</i> as novel diagnostic biomarkers and potential therapeutic targets for HF. These genes are closely related to the immune microenvironment, providing new insights into the early diagnosis, treatment, and mechanistic exploration of HF.
Authors
- Qiang Fu (ORCID: https://orcid.org/0009-0004-8504-3292)
- Shuyan Qin
- Cunjing Yu
- Jingyun Jin (ORCID: https://orcid.org/0009-0000-4814-4597)
- Hongjin Wu (ORCID: https://orcid.org/0009-0006-5698-9243)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Nanyang Institute of Technology (CN)
- Nanyang Medical College (CN)
- Beijing Haidian Hospital (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-05-08
- DOI
- https://doi.org/10.3389/fmolb.2025.1580880
- Citations
- 2
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 2.78