Mechanism of hedysari radix praeparata cum melle and curcumae rhizoma herb pair in colitis-associated colorectal cancer through the MAPK/NF-κB signaling pathway: an investigation in vivo and in vitro
HRCR not only suppresses the process of colonic inflammation and improves intestinal permeability but also relieves CAC by inhibiting the activated MAPK/NF-kB signalling cascade to alleviate CAC.
Authors
- Maomao Wang (ORCID: https://orcid.org/0000-0003-0305-1834)
- Yugui Zhang (ORCID: https://orcid.org/0000-0002-0269-3408)
- Feiyun Gao
- Zhe Wang (ORCID: https://orcid.org/0000-0003-4255-6763)
- Yuefeng Li (ORCID: https://orcid.org/0000-0002-5557-1682)
- Cui Ma (ORCID: https://orcid.org/0000-0001-5603-5964)
- Xingke Yan (ORCID: https://orcid.org/0000-0001-9638-7200)
- Zhuanhong Zhang
- Dingcai Ma
- Ting Liu (ORCID: https://orcid.org/0000-0002-5824-3975)
- Yanjun Wang (ORCID: https://orcid.org/0000-0001-6121-8706)
Institutions
- Gansu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Chemistry
- Published
- 2025-05-08
- DOI
- https://doi.org/10.3389/fchem.2025.1551722
- Citations
- 2
- Primary Topic
- Chromatography in Natural Products
- Type
- article
- Field-Weighted Citation Impact
- 1.50
Funders
- National Natural Science Foundation of China
- Gansu Education Department