Baicalin enhances respiratory mucosal immunity by modulating antiviral protein expression and T-cell homeostasis during H9N2 infection
These dual protective effects highlight baicalin's potential as a natural therapeutic strategy for improving mucosal immunity against vaccine-resistant influenza viruses such as H9N2, contributing valuable insights into plant-derived immunomodulatory approaches against emerging zoonotic viral threats.
Authors
- Xuguang Jiang (ORCID: https://orcid.org/0000-0002-8543-1613)
- Qian Zhang (ORCID: https://orcid.org/0000-0002-3004-4798)
- Haotong Guo
- Zhenyi Liu (ORCID: https://orcid.org/0009-0004-6677-3994)
- Yan Zhi (ORCID: https://orcid.org/0009-0002-3806-1055)
Institutions
- Qingdao University (CN)
- Yuhuangding Hospital (CN)
- Beijing University of Agriculture (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1593691
- Citations
- 2
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.71