Spin Bias in randomized controlled trials of botulinum toxin for bruxism management: a meta-epidemiologic study
Applying BTX into the temporalis did not reduce muscle activity and the results for masseter injections remain controversial. It seems that BTX-A injections can reduce pain from two weeks to one year. It is not possible to have certainty about the efficacy and safety of using BTX-A to reduce pain and bruxism events.
Authors
- Graziela De Luca Canto (ORCID: https://orcid.org/0000-0002-7986-8317)
- Thaís Marques Simek Vega Gonçalves (ORCID: https://orcid.org/0000-0002-0510-2140)
- Cristine Miron Stefani (ORCID: https://orcid.org/0000-0003-4712-9779)
- Ana Carolina Pereira Nunes Pinto (ORCID: https://orcid.org/0000-0002-1505-877X)
- Virgínia Fernandes Moça Trevisani (ORCID: https://orcid.org/0000-0002-7180-6285)
- Patrícia Pauletto (ORCID: https://orcid.org/0000-0002-1762-7059)
- Carlos Flores‐Mir (ORCID: https://orcid.org/0000-0002-0887-9385)
- Nelson Carvas (ORCID: https://orcid.org/0000-0003-2168-8927)
Institutions
- Universidade de Brasília (BR)
- University of Alberta (CA)
- Universidade Federal de Santa Catarina (BR)
- Universidade Federal do Amapá (BR)
- Iberoamerican Cochrane Centre (ES)
- Universidade de Santo Amaro (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- BMC Medical Research Methodology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1186/s12874-025-02547-9
- Primary Topic
- Temporomandibular Joint Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico