Preconceptional treatment with açaí juçara ( <i>Euterpe edulis</i> Martius) in advanced-age female rats did not interfere with metabolic parameters and redox balance during pregnancy
The consumption of açaí has been shown to be beneficial to health. This study aimed to evaluate the effects of juçara açai (JU, <i>Euterpe edulis Martius</i>) administration before gestation on the biometric, metabolic, and oxidative status in pregnant rats of advanced maternal age. Healthy female Wistar rats were treated with JU pulp via gavage from postnatal day 168 to 210. After treatment, the rats were mated, and during the 20 days of pregnancy, they were evaluated for body weight (BW), glucose tolerance, adipose tissue and liver weight, the lipid profile, and hepatic oxidative status. At birth, the offspring were weighed and counted. It was observed that JU reduced just maternal glycaemia. The maternal preconceptional treatment did not affect offspring BW. These results suggest that JU could be a safe nutritional intervention during the preconception period in advanced maternal age.
Authors
- Larissa Rugila dos Santos Stopa (ORCID: https://orcid.org/0000-0003-2420-3577)
- Karla Bigetti Guergoletto (ORCID: https://orcid.org/0000-0002-8285-2711)
- M. Rodrigues (ORCID: https://orcid.org/0000-0003-0007-9241)
- Ernane Torres Uchôa (ORCID: https://orcid.org/0000-0003-1295-5333)
- Graziela Scalianti Ceravolo (ORCID: https://orcid.org/0000-0001-7558-6294)
- Rhauany Pelisson Guergolette
- Glaura Scantamburlo Alves Fernandes (ORCID: https://orcid.org/0000-0002-6043-1131)
- Brenda Francisconi Diaz (ORCID: https://orcid.org/0009-0008-1998-6099)
- Fernando H. Borges (ORCID: https://orcid.org/0000-0002-7602-4119)
Institutions
- Universidade Estadual de Londrina (BR)
Publication Details
- Journal
- Archives of Physiology and Biochemistry
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1080/13813455.2025.2497260
- Primary Topic
- Antioxidant Activity and Oxidative Stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Secretário de Ciência, Tecnologia e Ensino Superior, Governo do Estado de Parana
- Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul
- Universidade Estadual de Londrina