Bradycardia, Renal Failure, Atrioventricular Nodal Blockade, Shock, and Hyperkalemia (BRASH) Syndrome Triggered by Missed Dialysis: A Case Report

Bradycardia, renal failure, atrioventricular (AV) nodal blocker usage, shock, and hyperkalemia are the hallmarks of BRASH syndrome, a complex medical emergency. Despite having a high mortality rate, BRASH syndrome is underdiagnosed and frequently develops from the combined effects of renal failure and drug toxicity. Here, we present the case of an 86-year-old woman with end-stage renal disease (ESRD) who developed BRASH syndrome due to missed dialysis sessions, exacerbated by low-dose beta-blocker therapy. This case emphasizes how crucial it is to identify BRASH syndrome early, treat it quickly, and address its untoward events to avoid fatalities.

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Journal
Cureus
Published
2025-05-08
DOI
https://doi.org/10.7759/cureus.83713
Citations
1
Primary Topic
Renal function and acid-base balance
Type
article
Field-Weighted Citation Impact
1.43
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article

Bradycardia, Renal Failure, Atrioventricular Nodal Blockade, Shock, and Hyperkalemia (BRASH) Syndrome Triggered by Missed Dialysis: A Case Report

Sai Karthik Kommineni, Neethu Vedantam, Kesava Manikanta Achuta, Venkata Vedantam et al.
1 citations
Cureus
Renal function and acid-base balance
1.43
article

Bradycardia, Renal Failure, Atrioventricular Nodal Blockade, Shock, and Hyperkalemia (BRASH) Syndrome Triggered by Missed Dialysis: A Case Report

Sai Karthik Kommineni, Neethu Vedantam, Kesava Manikanta Achuta, Venkata Vedantam, Kyasa S Venisha
article en
1 citations

Abstract

Bradycardia, renal failure, atrioventricular (AV) nodal blocker usage, shock, and hyperkalemia are the hallmarks of BRASH syndrome, a complex medical emergency. Despite having a high mortality rate, BRASH syndrome is underdiagnosed and frequently develops from the combined effects of renal failure and drug toxicity. Here, we present the case of an 86-year-old woman with end-stage renal disease (ESRD) who developed BRASH syndrome due to missed dialysis sessions, exacerbated by low-dose beta-blocker therapy. This case emphasizes how crucial it is to identify BRASH syndrome early, treat it quickly, and address its untoward events to avoid fatalities.

CureusVol. 17(5)
East Tennessee State University (US)
Good health and well-being
Openalex Percentile: Top 20%
Renal function and acid-base balance
1.43
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