Stabilization of Hoogsteen H-bonds in G-quartet sheets by coordinated K<sup>+</sup> ion for enhanced efficiency in guanine-rich DNA nanomotor
These findings demonstrate that coordinated K<sup>+</sup> ion play a critical role in stabilizing the TE conformation of G-rich DNA nanomotors by promoting G-quadruplex rigidity and facilitating Hoogsteen H-bond formation. This enhanced stability is essential for efficient DNA nanomotor function in the DU-TE nanoswitching process.
Authors
- Abolfazl Barzegar (ORCID: https://orcid.org/0000-0002-1237-0848)
- Nastaran Tohidifar
Institutions
- Tabriz University of Medical Sciences (IR)
- University of Tabriz (IR)
Publication Details
- Journal
- Bioimpacts
- Published
- 2025-05-03
- DOI
- https://doi.org/10.34172/bi.30596
- Primary Topic
- Advanced biosensing and bioanalysis techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Tabriz