Correlation between HMGB1 expression and drug resistance and prognosis in patients with bladder urothelial carcinoma
HMGB1 is highly expressed in urinary bladder epithelial carcinoma, and chemotherapy drugs can effectively inhibit the expression of HMGB1. Inhibition of HMGB1 expression is helpful to inhibit the proliferation of tumor cells. Circulating HMGB1 mRNA expression levels are closely associated with tumor prognosis, with low-expression patients having a longer survival period.
Authors
- Zhang Chen (ORCID: https://orcid.org/0000-0003-1062-9278)
- Juanjuan Li (ORCID: https://orcid.org/0000-0003-4581-3788)
- Tianyu Liang
- Min Xu (ORCID: https://orcid.org/0000-0001-9455-9494)
- Liang Hu (ORCID: https://orcid.org/0000-0002-7796-8963)
Institutions
- Zhejiang University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1007/s12672-025-02466-7
- Citations
- 3
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 3.96
Funders
- Jinhua Science and Technology Bureau