Single-cell RNA Sequencing Analysis Reveals the Regulatory Functions of Copines Family Genes in Testicular Cancer Progression

This study revealed the potential molecular mechanism through which Copines family genes drove the progression of testicular cancer through regulating PI3K-Akt signaling pathway and cell cycle, providing a new target for the development of precision treatment targeting Copines family genes and prognostic assessment of the cancer.

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Publication Details

Journal
Endocrine Metabolic & Immune Disorders - Drug Targets
Published
2025-05-06
DOI
https://doi.org/10.2174/0118715303375462250430055914
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Single-cell RNA Sequencing Analysis Reveals the Regulatory Functions of Copines Family Genes in Testicular Cancer Progression

Kai Yu, Zhong Lin, Delun Huang, Nan Li et al.
Endocrine Metabolic & Immune Disorders - Drug Targets
Sarcoma Diagnosis and Treatment
article

Single-cell RNA Sequencing Analysis Reveals the Regulatory Functions of Copines Family Genes in Testicular Cancer Progression

Kai Yu, Zhong Lin, Delun Huang, Nan Li, Xuehong Zhu
article en

Abstract

This study revealed the potential molecular mechanism through which Copines family genes drove the progression of testicular cancer through regulating PI3K-Akt signaling pathway and cell cycle, providing a new target for the development of precision treatment targeting Copines family genes and prognostic assessment of the cancer.

Endocrine Metabolic & Immune Disorders - Drug TargetsVol. 25
Guangxi University (CN), Guangxi University of Chinese Medicine (CN), The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
Good health and well-being
Openalex Percentile: Top 85%
Sarcoma Diagnosis and Treatment
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