Development of Satranidazole HCl-Loaded Oral Nanoparticulate Formulation forColon Targeting and Colon Cancer Therapy Associated with Inflammatory BowelDisease
The Satranidazole-loaded nanoparticles, containing time- and pH-dependent polymers, successfully inhibited premature drug release in acidic environments and provided controlled release at colonic pH. Thus, this delivery system shows promise as an effective treatment for IBD, offering targeted drug release and reduced systemic toxicity.
Authors
- Ananta Choudhury (ORCID: https://orcid.org/0000-0002-6894-1670)
- Subhabrota Majumdar (ORCID: https://orcid.org/0000-0002-1547-1273)
- Debgopal Ganguly
Institutions
- University of Health and Allied Sciences (GH)
- Assam Down Town University (IN)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2025-05-07
- DOI
- https://doi.org/10.2174/0113816128368738250414070421
- Citations
- 1
- Primary Topic
- Drug Solubulity and Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.79