A Plasma Metabolic Signature to Diagnose Pulmonary Tuberculosis and Monitor Treatment Response

The plasma Kyn/Trp ratio and retinol represents a promising metabolic signature that could advance TB diagnostics.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2025-05-08
DOI
https://doi.org/10.1093/infdis/jiaf240
Citations
6
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
8.38
Controls
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article

A Plasma Metabolic Signature to Diagnose Pulmonary Tuberculosis and Monitor Treatment Response

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The Journal of Infectious Diseases
Tuberculosis Research and Epidemiology
8.38
article

A Plasma Metabolic Signature to Diagnose Pulmonary Tuberculosis and Monitor Treatment Response

Laura Donnelly, Lisa Elon, Azhar Nizam, Matthew James Magee, Bezalam Tesfaye, Jeffrey Michael Collins, Thomas R. Ziegler, Mary M. Nellis, Sara C. Auld, Rebecca F. Goldstein, Melanie Quezada, Azeb Tarekegn, Loren E. Sasser, Shunsuke Sakai, Paul Ogongo, Nahom Getachew, Tawania Fergus, Nazir Ismail, Nestani Tukvadze, Lisa Sharling, Cheryl L. Day, Samuel Bayu, Meghan Franczek, Andrea Knežević, Wendy Whatney, Dean P. Jones, Anirudh Rao, Seegar Swanson, Russell Ryan Kempker, Salim Allana, Max S. Y. Lau, Shirin Jabbarzadeh, Daniel L. Barber, Devin Columbus, Jenna Daniel, N. Sarita Shah, Daniel Mussa, Melat Gebre-Medhin, Liya Wassie, Lance Allyn Waller, Yonas Abebe, Jemal Hussein, Abraham Aseffa, Dawn L. Comeau, Susan M. Ray, Keith D. Kauffman, Jyothi Rengarajan, Henry M. Blumberg, Nandakumar S. Narayanan, Hao Wu, Alemayehu Geletu, Angela Campbell, Alemayehu Kifle, Kidist Bobosha, Selam Jemberu, Mitin Wendaferew, Zenebech Assefa, Selam Dechasa, Firaol Wagari, Firaol Degaga, Rediet Zerihun, Mekdelawit Wondiyfraw, Meaza Zewdu, Ruth Mekonnen, Fisseha Mulate, Eleni Zeleke, Dawit Tayachew Bere, Million Legesse, Yunyun Chen, J. Ernst, Anthony Tran, Neel Gandhi, Tsegaye Hailu, James C.M. Brust, Sebsibe Neway, Edom Girma, Mahlet Mekuria, Gebeyehu Assefa, Medina Hamza, H Solomon, Daniel Getachew, Ranjna Madan Lala, Zewdu Solomon, Misker Kedir, Emebet Haile, Daniel Degefu, Bezawit Dinberu, Gutema Jebe
article en
6 citations

Abstract

The plasma Kyn/Trp ratio and retinol represents a promising metabolic signature that could advance TB diagnostics.

The Journal of Infectious DiseasesVol. 232(3)
National Institutes of Health (US), Albert Einstein College of Medicine (US), Emory University (US), Swiss Tropical and Public Health Institute (CH), University of California, San Francisco (US), University of the Witwatersrand (ZA), National Center for Tuberculosis and Lung Disease (GE), National Institute of Allergy and Infectious Diseases (US), Armauer Hansen Research Institute (ET)
Good health and well-being
Openalex Percentile: Top 2%
Tuberculosis Research and Epidemiology
8.38
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