Synovial fluid alpha‐2‐macroglobulin, gelsolin and lubricin distinguish between osteoarthritic and healthy equine joints
The upregulation of pregnancy zone protein and alpha-2-macroglobulin in OA joints motivates investigation into their function in OA and development of reagents for quantification. Several proteins with differential abundance in OA SF, including gelsolin and lubricin, were measured and may have diagnostic utility.
Authors
- Erica J. Secor (ORCID: https://orcid.org/0000-0002-9091-5444)
- Marshall J. Colville (ORCID: https://orcid.org/0000-0002-5397-8382)
- Machiel P. Ysebaert (ORCID: https://orcid.org/0000-0002-7484-915X)
- Sydney J. Womack
- Heidi L. Reesink (ORCID: https://orcid.org/0000-0001-8534-8839)
Institutions
- Cornell University (US)
- New York State College of Veterinary Medicine (US)
- University of California, Davis (US)
- Colorado State University (US)
Publication Details
- Journal
- Equine Veterinary Journal
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1111/evj.14511
- Primary Topic
- Veterinary Equine Medical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American College of Veterinary Surgeons Foundation
- National Institutes of Health
- Clinical and Translational Science Center, Weill Cornell Medical College