High Resolution Imaging and Fixation Analysis of Eccentric Preferred Retinal Loci in Macular Diseases
Participants adopt eccentric PRLs with hyporeflective cones and reduced sensitivity despite more sensitive and normal-appearing cones at greater eccentricities, suggesting that foveal proximity is prioritized over cone integrity in establishing a PRL. Fixation stability was similar among the four participants with eccentric fixation and those with RP, indicating that small shifts in the PRL from the anatomic fovea in our participants do not make fixation less stable.
Authors
- John S. Duncan (ORCID: https://orcid.org/0000-0002-1373-0681)
- Nicholas Rinella (ORCID: https://orcid.org/0000-0003-4894-4273)
- Katharina G. Foote
- Hao Zhou (ORCID: https://orcid.org/0000-0003-0068-5102)
- Ethan Bensinger
- Austin Roorda (ORCID: https://orcid.org/0000-0002-3785-0848)
- Ruikang K. Wang (ORCID: https://orcid.org/0000-0001-5169-8822)
- Jessica Wong (ORCID: https://orcid.org/0000-0001-7109-919X)
- Olubayo U Kolawole
Institutions
- University of California, San Francisco (US)
- University of Washington (US)
- University of California, Berkeley (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1167/iovs.66.5.18
- Citations
- 2
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- Larry L. Hillblom Foundation
- Research to Prevent Blindness
- Biogen
- University of Washington
- Hope For Vision
- That Man May See
- Carl Zeiss Meditec AG
- National Institutes of Health
- Allergan