Analysis of alterations in the composition of the intestinal microbiota in frail older individuals
The gut microbiota of frail older individuals underwent significant changes in structural composition, and the presence of Escherichia-Shigella may be a diagnostic marker for debilitating diseases. These findings provide an essential clinical reference value for developing methods for preventing or alleviating frailty based on specific microbial communities.
Authors
- Lamei Yang
- Xiaoli Yan (ORCID: https://orcid.org/0000-0002-6512-2338)
- Chuan Zhang (ORCID: https://orcid.org/0000-0001-8579-728X)
- Lu Gong
- Shilan Luo
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1371/journal.pone.0320918
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 0.00