Altered aminoacid and lipid metabolism in a rat orofacial inflammation model determined by omics approach: potential role in trigeminal sensitisation
Integrated joint pathway analysis of metabolomic and transcriptomic data provides a useful approach to determine pathophysiological mechanisms of trigeminal sensitization and identify novel drug targets for orofacial pain and headaches.
Authors
- Krisztina Takács-Lovász
- Gellért Karvaly (ORCID: https://orcid.org/0000-0003-2468-5633)
- Violetta Mohos (ORCID: https://orcid.org/0000-0001-6248-060X)
- Tímea Aczél (ORCID: https://orcid.org/0000-0001-8596-4180)
- Zsuzsanna Helyes (ORCID: https://orcid.org/0000-0003-2435-4367)
- Michał Ciborowski (ORCID: https://orcid.org/0000-0003-3729-0518)
- Joanna Godzień (ORCID: https://orcid.org/0000-0002-9477-057X)
- Róbert Farkas (ORCID: https://orcid.org/0000-0002-9138-7567)
- József Kun (ORCID: https://orcid.org/0000-0001-9607-305X)
- Kata Bölcskei (ORCID: https://orcid.org/0000-0002-3008-4538)
- Máté Harmath
- Jennet Pirkuliyeva
Institutions
- Semmelweis University (HU)
- Medical University of Białystok (PL)
- National Center for Epidemiology (HU)
- University of Pecs (HU)
Publication Details
- Journal
- The Journal of Headache and Pain
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1186/s10194-025-02024-0
- Primary Topic
- Biochemical effects in animals
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Hungarian Scientific Research Fund
- Pécsi Tudományegyetem
- Nemzeti Kutatási Fejlesztési és Innovációs Hivatal