Metabolic characteristics of benign and malignant pulmonary nodules and establishment of invasive lung adenocarcinoma model by high-resolution mass spectrometry
Met-Thr depletion inversely correlates with malignancy progression, while eight-metabolite signatures demonstrate diagnostic potential for preoperative infiltration assessment in nodular adenocarcinoma.
Authors
- Yu Hou (ORCID: https://orcid.org/0000-0001-7875-7087)
- Yuenan Wang (ORCID: https://orcid.org/0000-0001-6280-6956)
- Junbao Zhang (ORCID: https://orcid.org/0000-0003-1335-752X)
- Ruifang Pang (ORCID: https://orcid.org/0000-0003-3225-1106)
- Zhihan Zhang (ORCID: https://orcid.org/0000-0003-4096-9994)
- Yuying Liu (ORCID: https://orcid.org/0000-0003-3848-9254)
- Ping Xu
Institutions
- Peking University (CN)
- Fudan University (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1186/s12885-025-14253-2
- Citations
- 1
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Natural Science Foundation of Guangdong Province
- Peking University
- Science, Technology and Innovation Commission of Shenzhen Municipality