Comparative study on drug encapsulation and release kinetics in extracellular vesicles loaded with snake venom L - amino acid oxidase
In conclusion, the coincubation method preserves EV membrane integrity, enabling sustained drug release, making it a promising strategy for targeted drug delivery applications. This study highlights plasma-derived EVs as innovative carriers for therapeutic delivery.
Authors
- Vinutha Bhat (ORCID: https://orcid.org/0000-0002-9457-9492)
- Shankar M Bakkannavar (ORCID: https://orcid.org/0000-0001-6599-7014)
- K. Sreedhara Ranganath Pai (ORCID: https://orcid.org/0000-0002-2017-9533)
- Krishna Sharan (ORCID: https://orcid.org/0000-0002-7949-1708)
- Divya Ramesh (ORCID: https://orcid.org/0000-0002-4362-584X)
Institutions
- Manipal Academy of Higher Education (IN)
- K S Hegde Medical Academy (IN)
- Kasturba Medical College, Manipal (IN)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1186/s40360-025-00938-8
- Citations
- 7
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- Kasturba Medical College, Manipal
- Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education