New phenazines from Taibai mountain-derived <i>Streptomyces xanthophaeus</i> A54
Four phenazineswere isolated from the Taibai mountain-derived <i>Streptomyces xanthophaeus</i> A54, among which Taibphenazine A (<b>1</b>) and Taibphenazine B (<b>2</b>) are new compounds. Comprehensive spectroscopic analyses, including HRESIMS, NMR, ECD calculations, and optical rotation value, were employed to elucidate the structures of these compounds. Taibphenazine B showed considerable anti-influenza A virus activity (IC<sub>50</sub>=27.07 μM), which was similar to the positive control ribavirin (IC<sub>50</sub>=24.20 μM).
Authors
- Xue Yang (ORCID: https://orcid.org/0000-0002-4960-0950)
- Lukuan Hou (ORCID: https://orcid.org/0009-0007-4531-351X)
- Shuyao Wang (ORCID: https://orcid.org/0000-0001-5855-1508)
- Wenli Li (ORCID: https://orcid.org/0000-0003-1598-3217)
Institutions
- Northwest A&F University (CN)
Publication Details
- Journal
- Natural Product Research
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1080/14786419.2025.2502141
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China