Treatment with oxfendazole increased levels of cardiac troponin I in pigs naturally infected with Taenia solium cysticercosis
This study shows that OXF treatment of pigs with T. solium cysticercosis results in increased concentration of cTnI possibly due to the cardiac damage/inflammatory response following treatment as the cysts degenerate/calcify. This makes cTnI a very good biomarker for cardiac injury/damage following treatment in pigs with cysticercosis.
Authors
- Kabemba E. Mwape (ORCID: https://orcid.org/0000-0002-6788-2592)
- Chummy Sikasunge (ORCID: https://orcid.org/0000-0002-5564-2655)
- M.C. Sitali (ORCID: https://orcid.org/0000-0003-4406-1115)
- Andrea Sylvia Winkler (ORCID: https://orcid.org/0000-0003-3131-6983)
- Isaac K. Phiri (ORCID: https://orcid.org/0000-0002-7060-2395)
- Racheal Mwenda (ORCID: https://orcid.org/0000-0002-7933-1325)
- Veronika Schmidt (ORCID: https://orcid.org/0000-0002-6108-2586)
- Mwelwa Chembensofu
- Martin Chitolongo Simuunza (ORCID: https://orcid.org/0000-0001-6621-7470)
- Maxwell Masuku
- Chibeza Zulu (ORCID: https://orcid.org/0009-0006-5151-8493)
Institutions
- University of Oslo (NO)
- TUM Klinikum (DE)
- University of Zambia (ZM)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1371/journal.pone.0321735
- Citations
- 1
- Primary Topic
- Parasitic infections in humans and animals
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Bundesministerium für Bildung und Forschung