Causal relationship between schizophrenia and five types of dementia: A bidirectional two-sample Mendelian randomization study
Our findings suggest that schizophrenia may be a risk factor for all-cause dementia, Alzheimer's disease, and vascular dementia, but no dementia of any kind was found to be a risk factor for schizophrenia. Our study provides insights into the potential genetic relationship between schizophrenia and dementia.
Authors
- Xuan Liang (ORCID: https://orcid.org/0000-0002-0792-3751)
- Tao Feng (ORCID: https://orcid.org/0000-0003-2527-2443)
- Jingyue Liu (ORCID: https://orcid.org/0000-0002-2267-1433)
- Shizhe Deng (ORCID: https://orcid.org/0000-0002-7566-9679)
- Jiangwei Shi
- Zhihong Meng (ORCID: https://orcid.org/0000-0003-1397-3138)
- Bifang Zhuo
Institutions
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1371/journal.pone.0322752
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82