SA supplementation during lactation promotes learning and memory by reducing H3K27me3 levels
Consequently, our study finds that decreased H3K27me3 promotes the glutamate-glutamine cycle under the influence of SA, thereby contributing to enhanced learning and memory. The potential implication of our findings is that SA in early life may contribute to the optimization of children's comprehensive cognitive function.
Authors
- Chengqing Huang
- Ming Nie (ORCID: https://orcid.org/0000-0002-0259-3247)
- Mengmeng Wang (ORCID: https://orcid.org/0000-0001-5379-5773)
- Heyujia Zhang
- Xiaozhen Gu
- Kun Wang (ORCID: https://orcid.org/0000-0003-3414-2552)
- Huili Wang (ORCID: https://orcid.org/0000-0001-6852-8002)
- Changqing Li
- Shu Ai
Institutions
- Macau University of Science and Technology (MO)
- Hefei University of Technology (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1016/j.jare.2025.04.047
- Primary Topic
- Neuroscience of respiration and sleep
- Type
- article
- Field-Weighted Citation Impact
- 0.00