Identification of a translatable animal model for dry eye disease using comparative analysis of tear proteins across species
The pig exhibited the highest similarity to humans in tear protein analysis among non-primate mammals, suggesting that the porcine model may be the most translational for DED research.
Authors
- Ana González-López
- Adrián Guerrero-Moreno
- Laura Ortega-Llamas
- Miguel González‐Andrades (ORCID: https://orcid.org/0000-0003-4632-1267)
- Sascha Fauser (ORCID: https://orcid.org/0000-0001-6375-7682)
- David Alba-Molina (ORCID: https://orcid.org/0000-0003-2128-3006)
- Mercè Granados (ORCID: https://orcid.org/0000-0003-2032-3352)
- Yolanda Jiménez (ORCID: https://orcid.org/0000-0002-1607-2717)
- Mario Blanco-Blanco
- Christoph Ullmer (ORCID: https://orcid.org/0000-0002-1044-6722)
- Stephen C. Pflugfelder (ORCID: https://orcid.org/0000-0002-9341-3482)
- Mayelín Pérez-Perdomo
Institutions
- Roche (Switzerland) (CH)
- Baylor College of Medicine (US)
- Instituto Maimónides de Investigación Biomédica de Córdoba (ES)
- University of Córdoba (ES)
Publication Details
- Journal
- The Ocular Surface
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1016/j.jtos.2025.05.004
- Citations
- 2
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 3.76