Treatment Sequences in BRAF-V600–Mutated NSCLC: First-Line Targeted Therapy Versus First-Line (Chemo-) Immunotherapy

Targeted or IO-based first-line treatment of BRAF-V600-mutated NSCLC has similar survival outcomes. Sex and PD-L1 status may support decision-making at the individual patient level.

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Publication Details

Journal
Journal of Thoracic Oncology
Published
2025-05-08
DOI
https://doi.org/10.1016/j.jtho.2025.04.016
Citations
14
Primary Topic
Synthesis and biological activity
Type
article
Field-Weighted Citation Impact
13.10
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article

Treatment Sequences in BRAF-V600–Mutated NSCLC: First-Line Targeted Therapy Versus First-Line (Chemo-) Immunotherapy

Martin Sebastian, Petros Christopoulos, Nikolaj Frost, Martin Wermke et al.
14 citations
Journal of Thoracic Oncology
Synthesis and biological activity
13.10
article

Treatment Sequences in BRAF-V600–Mutated NSCLC: First-Line Targeted Therapy Versus First-Line (Chemo-) Immunotherapy

Martin Sebastian, Petros Christopoulos, Nikolaj Frost, Martin Wermke, Maximilian Rost, Hans‐Georg Kopp, Martin Schüler, Martin Reck, Christin Assmann, Frank Griesinger, Anna Kron, Felix Carl Saalfeld, Matthias Scheffler, Moritz Hilbrandt, Franziska Herster, Julia Roeper, Marcel Wiesweg, Anna Rasokat, Franziska Glanemann, Albrecht Stenzinger, Ali Alaffas, Jürgen Wolf, Jonas Kulhavy, Cornelia Kropf-Sanchen
article en
14 citations

Abstract

Targeted or IO-based first-line treatment of BRAF-V600-mutated NSCLC has similar survival outcomes. Sex and PD-L1 status may support decision-making at the individual patient level.

Journal of Thoracic OncologyVol. 20(9)
Essen University Hospital (DE)
Good health and well-being
Openalex Percentile: Top 1%
Synthesis and biological activity
13.10
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Treatment Sequences in BRAF-V600–Mutated NSCLC: First-Line Targeted Therapy Versus First-Line (Chemo-) Immunotherapy — Martin Sebastian, Petros Christopoulos, et al. · Journal of Thoracic Oncology (2025) | TGRS Research Map | TGRS