Reward Sensitivity in Patients Receiving Opioid Agonist and Antagonist Treatment for Opioid Use Disorder: An Observational Study
These data support an association between OUD and reduced well-being irrespective of opioid agonist or antagonist treatment, highlighting patients' need for psychosocial support and/or adjunct interventions. Major detrimental effects of naltrexone treatment on well-being seem unlikely from these and previous results.
Authors
- Siri Leknes (ORCID: https://orcid.org/0000-0002-6667-4601)
- Mads L. Pedersen (ORCID: https://orcid.org/0000-0001-5240-7783)
- Philipp Lobmaier (ORCID: https://orcid.org/0000-0003-3066-5583)
- Marie Eikemo (ORCID: https://orcid.org/0000-0001-5103-919X)
- Kristin Klemmetsby Solli (ORCID: https://orcid.org/0000-0003-4622-2947)
- Martin Trøstheim (ORCID: https://orcid.org/0000-0002-6021-6714)
- Lars Tanum (ORCID: https://orcid.org/0000-0003-4001-6325)
- Bente Margrethe Weimand (ORCID: https://orcid.org/0000-0003-1800-7318)
- M. Roland
- Lennja Majid Hama
Institutions
- Oslo University Hospital (NO)
- OsloMet – Oslo Metropolitan University (NO)
- University of Oslo (NO)
- Akershus University Hospital (NO)
- Vestre Viken Hospital Trust (NO)
- University of South-Eastern Norway (NO)
- Sykehuset i Vestfold (NO)
Publication Details
- Journal
- Biological Psychiatry Cognitive Neuroscience and Neuroimaging
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1016/j.bpsc.2025.04.013
- Primary Topic
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Alkermes
- Universitetet i Oslo
- Norges Forskningsråd
- Akershus Universitetssykehus
- Helse Sør-Øst RHF