Evaluation of selected inflammatory markers in cats with feline infectious peritonitis before and after therapy

Our findings demonstrate that successful treatment of FIP leads to highly significant changes in most clinicopathological parameters, including haemogram-derived inflammatory markers. The latter could offer a simple, inexpensive and readily available alternative to the more commonly used acute phase proteins for monitoring FIP treatment. Successful therapy leads to a significant decrease in haptoglobin and an increase in tumour necrosis factor-α. In our study, cats with an unfavourable outcome showed a marked increase in lactate dehydrogenase activity before therapy, suggesting that this parameter could be a promising prognostic factor in larger studies.

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Publication Details

Journal
BMC Veterinary Research
Published
2025-05-09
DOI
https://doi.org/10.1186/s12917-025-04731-x
Citations
3
Primary Topic
Animal Virus Infections Studies
Type
article
Field-Weighted Citation Impact
3.58

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article

Evaluation of selected inflammatory markers in cats with feline infectious peritonitis before and after therapy

Darja Pavlin, Martina Krofič Žel, Nataša Tozon, Saša Koprivec et al.
3 citations
BMC Veterinary Research
Animal Virus Infections Studies
3.58
article

Evaluation of selected inflammatory markers in cats with feline infectious peritonitis before and after therapy

Darja Pavlin, Martina Krofič Žel, Nataša Tozon, Saša Koprivec, Alenka Nemec Svete, Lina Tršar, Marjeta Štrljič
article en
3 citations

Abstract

Our findings demonstrate that successful treatment of FIP leads to highly significant changes in most clinicopathological parameters, including haemogram-derived inflammatory markers. The latter could offer a simple, inexpensive and readily available alternative to the more commonly used acute phase proteins for monitoring FIP treatment. Successful therapy leads to a significant decrease in haptoglobin and an increase in tumour necrosis factor-α. In our study, cats with an unfavourable outcome showed a marked increase in lactate dehydrogenase activity before therapy, suggesting that this parameter could be a promising prognostic factor in larger studies.

BMC Veterinary ResearchVol. 21(1)
University of Ljubljana (SI)
Javna Agencija za Raziskovalno Dejavnost RS
Zero hunger
Openalex Percentile: Top 8%
Animal Virus Infections Studies
3.58
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Evaluation of selected inflammatory markers in cats with feline infectious peritonitis before and after therapy — Darja Pavlin, Martina Krofič Žel, et al. · BMC Veterinary Research (2025) | TGRS Research Map | TGRS