Antiemetic effect of acupressure wristbands for GLP-1 medication associated nausea
Although not a controlled trial, this pilot, proof of concept, pragmatic study suggests that ACW may offer a safe, self-administered, reusable, and drug-free option for managing GLP-1a associated nausea.ACW's nausea reducing effect was seen in over 80 % of episodes, and remained consistent throughout the study period. One third of participants experienced relief within 5 min of wearing ACW in the first three weeks. Given the relatively small sample size of the population, further large-scale investigations are justified. Nausea is common in day-to-day real-world use of GLP-1as, and our results suggest that using ACW may provide a first-line therapeutic intervention used ad libitum to tame a disruptive symptom, improve day-to-day well-being, and positively impact a person's treatment journey on GLP-1a.
Authors
- A. Reyes (ORCID: https://orcid.org/0000-0002-2413-7103)
- Nawfal W. Istfan (ORCID: https://orcid.org/0000-0001-7163-8309)
- Florencia Ziemke
- Soufiane Belarj
- Jem Esguerra
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Palm Beach Neurology (US)
- Jupiter Medical Center (US)
Publication Details
- Journal
- Obesity Pillars
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1016/j.obpill.2025.100178
- Primary Topic
- Nausea and vomiting management
- Type
- article
- Field-Weighted Citation Impact
- 0.00