Antiemetic effect of acupressure wristbands for GLP-1 medication associated nausea

Although not a controlled trial, this pilot, proof of concept, pragmatic study suggests that ACW may offer a safe, self-administered, reusable, and drug-free option for managing GLP-1a associated nausea.ACW's nausea reducing effect was seen in over 80 % of episodes, and remained consistent throughout the study period. One third of participants experienced relief within 5 min of wearing ACW in the first three weeks. Given the relatively small sample size of the population, further large-scale investigations are justified. Nausea is common in day-to-day real-world use of GLP-1as, and our results suggest that using ACW may provide a first-line therapeutic intervention used ad libitum to tame a disruptive symptom, improve day-to-day well-being, and positively impact a person's treatment journey on GLP-1a.

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Publication Details

Journal
Obesity Pillars
Published
2025-05-08
DOI
https://doi.org/10.1016/j.obpill.2025.100178
Primary Topic
Nausea and vomiting management
Type
article
Field-Weighted Citation Impact
0.00
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article

Antiemetic effect of acupressure wristbands for GLP-1 medication associated nausea

A. Reyes, Nawfal W. Istfan, Florencia Ziemke, Soufiane Belarj et al.
Obesity Pillars
Nausea and vomiting management
article

Antiemetic effect of acupressure wristbands for GLP-1 medication associated nausea

A. Reyes, Nawfal W. Istfan, Florencia Ziemke, Soufiane Belarj, Jem Esguerra
article en

Abstract

Although not a controlled trial, this pilot, proof of concept, pragmatic study suggests that ACW may offer a safe, self-administered, reusable, and drug-free option for managing GLP-1a associated nausea.ACW's nausea reducing effect was seen in over 80 % of episodes, and remained consistent throughout the study period. One third of participants experienced relief within 5 min of wearing ACW in the first three weeks. Given the relatively small sample size of the population, further large-scale investigations are justified. Nausea is common in day-to-day real-world use of GLP-1as, and our results suggest that using ACW may provide a first-line therapeutic intervention used ad libitum to tame a disruptive symptom, improve day-to-day well-being, and positively impact a person's treatment journey on GLP-1a.

Obesity PillarsVol. 15
Brigham and Women's Hospital (US), Harvard University (US), Palm Beach Neurology (US), Jupiter Medical Center (US)
Openalex Percentile: Top 83%
Nausea and vomiting management
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Antiemetic effect of acupressure wristbands for GLP-1 medication associated nausea — A. Reyes, Nawfal W. Istfan, et al. · Obesity Pillars (2025) | TGRS Research Map | TGRS