How narrow is narrow QRS in premature ventricular contractions? A novel variant of SCN5A-associated MEPPC

Gain-of-function mutations in the SCN5A gene may cause Multifocal Ectopic Purkinje-related premature Contractions (MEPPC) linked to Purkinje system hyperpolarization and dilated cardiomyopathy. [1] This case highlights the importance of genetic testing in diagnosing arrhythmias and tailoring antiarrhythmic therapy.

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Publication Details

Journal
HeartRhythm Case Reports
Published
2025-05-08
DOI
https://doi.org/10.1016/j.hrcr.2025.05.004
Primary Topic
Cardiac Arrhythmias and Treatments
Type
article
Field-Weighted Citation Impact
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article

How narrow is narrow QRS in premature ventricular contractions? A novel variant of SCN5A-associated MEPPC

Asude Durmaz, Oğuzhan Ekrem Turan, Emin Evren Özcan, Reşit Yiğit Yılancıoglu et al.
HeartRhythm Case Reports
Cardiac Arrhythmias and Treatments
article

How narrow is narrow QRS in premature ventricular contractions? A novel variant of SCN5A-associated MEPPC

Asude Durmaz, Oğuzhan Ekrem Turan, Emin Evren Özcan, Reşit Yiğit Yılancıoglu, Ayça Aykut, Sercan Karaoğlan
article en

Abstract

Gain-of-function mutations in the SCN5A gene may cause Multifocal Ectopic Purkinje-related premature Contractions (MEPPC) linked to Purkinje system hyperpolarization and dilated cardiomyopathy. [1] This case highlights the importance of genetic testing in diagnosing arrhythmias and tailoring antiarrhythmic therapy.

HeartRhythm Case ReportsVol. 11(7)
Dokuz Eylül University (TR), Ege University (TR)
Zero hunger
Openalex Percentile: Top 83%
Cardiac Arrhythmias and Treatments
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