A highly virulent BA-producing Burkholderia gladioli strain linked to a fatal foodborne outbreak in China, 2020
This outbreak highlights the dual threat of hypervirulent BA production and intrinsic multidrug resistance in B. gladioli. The absence of CLSI breakpoints for this pathogen complicates clinical susceptibility interpretations, yet YD01's resistance profile suggests limited therapeutic options in empirical treatment. Enhanced surveillance, species-specific antimicrobial guidelines, and rapid diagnostics targeting both bon and resistance genes are urgently needed to mitigate future risks.
Authors
- Jinrui Hu (ORCID: https://orcid.org/0000-0001-8982-9971)
- Weiqi Zhong
- Yucheng Xue
- Haijian Zhou (ORCID: https://orcid.org/0000-0002-8742-5399)
- Jing Bai (ORCID: https://orcid.org/0000-0001-8197-703X)
- Jinhui Zhang (ORCID: https://orcid.org/0000-0002-4476-7807)
- Zheng Xiao-hua
- Jinyue Liu (ORCID: https://orcid.org/0000-0002-0182-7670)
- Zhigang Cui
Institutions
- Heilongjiang Center for Tuberculosis Control and Prevention (CN)
- National Institute for Communicable Disease Control and Prevention (CN)
Publication Details
- Journal
- Infection Genetics and Evolution
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1016/j.meegid.2025.105760
- Citations
- 3
- Primary Topic
- Plant Pathogenic Bacteria Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.25
Funders
- National Key Research and Development Program of China