Intracranial pressure dynamics, cerebral autoregulation, and brain perfusion after decompressive craniectomy in malignant middle cerebral artery infarction: is there a role for invasive monitoring?
Invasive ICP-monitoring may provide prognostic information for long-term recovery in MMI patients post-DC. The study highlighted disease-specific optimal physiological intervals for ICP, PRx, CPP, and ΔCPPopt. Of particular interest, the autoregulatory variable, PRx, influenced the safe and dangerous ICP, CPP, and ∆CPPopt intervals.
Authors
- Anders Lewén (ORCID: https://orcid.org/0000-0003-4925-1348)
- Anders Hånell (ORCID: https://orcid.org/0000-0001-9369-3886)
- Teodor Svedung Wettervik (ORCID: https://orcid.org/0000-0002-4556-5721)
- Timothy Howells
- Per Enblad (ORCID: https://orcid.org/0000-0003-4364-1919)
- Modar Alhamdan (ORCID: https://orcid.org/0009-0003-3860-5742)
Institutions
- Uppsala University (SE)
Publication Details
- Journal
- Acta Neurochirurgica
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1007/s00701-025-06537-0
- Citations
- 1
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Akademiska Sjukhuset
- Uppsala Universitet