Targeting Stat3 with conditional knockout or PROTAC technology alleviates renal injury by Limiting pyroptosis
This work was supported by the National Key R&D Program (2022YFC2502503), the National Natural Science Foundation of China (No. 82270738), the National Natural Science Foundation of China (No. 82400806) and the Graduate Research and Practice Innovation Project of Anhui Medical University (YJS20230059).
Authors
- Rui Hou (ORCID: https://orcid.org/0000-0002-0348-8772)
- Mingfei Wu
- Ming-Lu Ji
- Chuan‐hui Xu
- Xiao-Guo Suo
- Wei Shao (ORCID: https://orcid.org/0000-0003-1763-9911)
- Shaoxi Diao
- Ju-tao Yu (ORCID: https://orcid.org/0000-0002-8888-9881)
- Jiagen Wen (ORCID: https://orcid.org/0000-0002-4375-6567)
- Lu Hao (ORCID: https://orcid.org/0000-0002-4305-7766)
- Qi Zhu (ORCID: https://orcid.org/0000-0001-7239-1854)
- Xiao‐Ming Meng (ORCID: https://orcid.org/0000-0002-1166-561X)
- Shuai-shuai Xie (ORCID: https://orcid.org/0000-0003-3751-2109)
- W. L. Chang
- Jinxin Che (ORCID: https://orcid.org/0000-0001-7202-9214)
- Chao Li (ORCID: https://orcid.org/0000-0003-1568-9704)
- Wenbin Wang (ORCID: https://orcid.org/0000-0003-3682-1858)
- Xin Chen (ORCID: https://orcid.org/0000-0002-9827-7731)
- Ying Chen (ORCID: https://orcid.org/0000-0003-0035-5656)
- Mengmeng Zhang (ORCID: https://orcid.org/0000-0001-7632-7702)
- Jianan Wang (ORCID: https://orcid.org/0009-0007-8301-780X)
- Nannan Ma (ORCID: https://orcid.org/0000-0002-8975-3337)
- Yuhang Dong
- Juan Jin (ORCID: https://orcid.org/0000-0003-3087-1555)
- Xiaowu Dong (ORCID: https://orcid.org/0000-0002-5717-5384)
- Danfeng Zhang
- X. Mao
Institutions
- Anhui Medical University (CN)
- JiangSu Armed Police General Hospital (CN)
- Anhui Provincial Hospital (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
- Zhejiang University of Technology (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- EBioMedicine
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1016/j.ebiom.2025.105739
- Citations
- 11
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 11.50
Funders
- National Natural Science Foundation of China
- Anhui Medical University