Clinical efficacy of 5-aminolevulinic acid photodynamic therapy combined with microneedling for vulvar lichen sclerosus
ALA-PDT combined with microneedling achieves rapid and sustained symptom remission, improves quality of life, and demonstrates excellent safety in refractory VLS. Early intervention (disease duration <1 year) correlates with superior therapeutic outcomes. This combination therapy represents a promising strategy for PDT-enhanced VLS management.
Authors
- Yayan Lin
- Hong Kang (ORCID: https://orcid.org/0000-0003-4487-225X)
- Honghui Zhang (ORCID: https://orcid.org/0000-0003-2403-4961)
- Chunying Xiao (ORCID: https://orcid.org/0000-0002-3847-715X)
- Xiukuan Xu
Institutions
- Zhangzhou Municipal Hospital of Fujian Province (CN)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1016/j.pdpdt.2025.104623
- Primary Topic
- Genital Health and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00