Direct thrombin inhibition during pulmonary vein isolation using pulsed field ablation
Bivalirudin reversibly inhibits circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation with a predictable antithrombotic response.1 Some reports have described its use during catheter-based arrhythmia ablation procedures using thermal energy, including pulmonary vein isolation (PVI) for atrial fibrillation (AF) treatment.2–5
Authors
- Antonio Asso
- Carlos López-Perales
- Naiara Calvo (ORCID: https://orcid.org/0000-0002-1889-3746)
- Beatriz Jáuregui (ORCID: https://orcid.org/0000-0001-9187-1773)
Institutions
- Universidad de Zaragoza (ES)
- Hospital Quirónsalud Barcelona (ES)
- Hospital Universitario Miguel Servet (ES)
Publication Details
- Journal
- HeartRhythm Case Reports
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1016/j.hrcr.2025.04.020
- Citations
- 1
- Primary Topic
- Cardiac Arrhythmias and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39