A randomized controlled trial of anodal transcranial direct current stimulation (A-tDCS) and olfactory training in persistent COVID-19 anosmia
This RCT demonstrates that combining A-tDCS with concurrent OT is able to restore the olfactory function in individuals suffering from persistent COVID-19 anosmia, with a durable effect. This safe and inexpensive treatment can therefore represent a suitable and widespread option for millions of individuals. These positive results also support the hypothesis that the brain olfactory networks are involved in the pathophysiology of COVID-19 anosmia.
Authors
- Fabio Bandini (ORCID: https://orcid.org/0000-0002-1104-459X)
- Laura Mori (ORCID: https://orcid.org/0000-0003-2762-8327)
- Carlo Trompetto (ORCID: https://orcid.org/0000-0003-3419-0669)
- Marta Ponzano (ORCID: https://orcid.org/0000-0003-4091-4686)
- Lucilla Vestito (ORCID: https://orcid.org/0000-0002-9141-895X)
Institutions
- Azienda Mobilità e Trasporti (IT)
- Ospedale Policlinico San Martino (IT)
- University of Genoa (IT)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1016/j.brs.2025.04.023
- Citations
- 1
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.46