Multi-dimensional characterization of cellular states reveals clinically relevant immunological subtypes and therapeutic vulnerabilities in ovarian cancer
Our comprehensive analysis of TME helps leveraging various immunological subtypes to highlight new directions and targets for the treatment of cancer.
Authors
- Jinyang Yu
- Jiwei Pan
- Juan Xu (ORCID: https://orcid.org/0000-0002-3709-4165)
- Tao Pan (ORCID: https://orcid.org/0000-0002-9244-9950)
- Ya Zhang (ORCID: https://orcid.org/0000-0002-5390-9053)
- Yongsheng Li (ORCID: https://orcid.org/0000-0003-1914-0727)
- Si Li (ORCID: https://orcid.org/0000-0001-7997-0904)
- Can Zhang (ORCID: https://orcid.org/0000-0002-4340-5118)
- Xia Li (ORCID: https://orcid.org/0000-0002-9794-2648)
- Meng Liu (ORCID: https://orcid.org/0000-0002-6960-3163)
- Qingyi Yang (ORCID: https://orcid.org/0009-0001-9836-4261)
- Yueying Gao (ORCID: https://orcid.org/0009-0003-3095-8228)
- Jiyu Guo
Institutions
- Harbin Medical University (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1186/s12967-025-06521-3
- Citations
- 1
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hainan Province
- Natural Science Foundation of Heilongjiang Province