Alterations in Cerebral Intrinsic Activity in First-Episode, Drug-Naive Patients With Major Depressive Disorder
Our study demonstrates that alterations of cerebral intrinsic activity may occur in the early course of MDD without interference from antidepressants. As these regions are crucial for the regulation of cognition, we speculate that these changes may subserve the disturbances of cognitive function in early MDD.
Authors
- Asma Ul Hussain
- Ali Tariq
- Bushra Imtiaz
- Fnu Shweta (ORCID: https://orcid.org/0000-0001-6634-6272)
- Yasmeen Ali (ORCID: https://orcid.org/0000-0002-3947-6482)
- FNU Partab
- Hafiza Sidra
- Hamail Hashmi
- Hamza Shahab
Institutions
- Chandka Medical College (PK)
- University of Health Sciences Lahore (PK)
- Drexel University (US)
Publication Details
- Journal
- Cureus
- Published
- 2025-05-08
- DOI
- https://doi.org/10.7759/cureus.83737
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00