Advancing the evaluation of radiation‐induced vaginal toxicity using ultrasound radiomics: Phantom validation and pilot clinical study
This phantom and pilot study demonstrated that ultrasound GLCM features can serve as reliable quantitative biomarkers for assessing radiation-induced vaginal toxicity in female patients receiving pelvic RT for GYN cancers. Implementing these biomarkers in clinical practice could enhance the objectivity of toxicity evaluations, leading to more consistent grading and better-informed follow-up care for patients.
Authors
- Deborah Marshall (ORCID: https://orcid.org/0000-0002-6675-7482)
- Joseph W. Shelton (ORCID: https://orcid.org/0000-0003-0426-8197)
- Emi Yoshida
- Himanshu Joshi (ORCID: https://orcid.org/0000-0003-0272-0733)
- Boran Zhou (ORCID: https://orcid.org/0000-0001-9774-2737)
- Tian Liu (ORCID: https://orcid.org/0000-0002-4932-2727)
- Jing Wang (ORCID: https://orcid.org/0000-0002-8491-4146)
- Xiaofeng Yang
Institutions
- Emory University (US)
- University of California, San Francisco (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Medical Physics
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1002/mp.17864
- Citations
- 1
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- National Institutes of Health