False-positive dengue IgM in <i>Streptobacillus moniliformis</i> rat-bite fever: the need to look beyond the rapid test—a case report

This case highlights the diagnostic challenge posed by cross-reactive dengue serology in RBF, emphasizing the need to avoid relying solely on IgM positivity for diagnosing dengue fever. Although comparatively less common, clinicians should be aware of non-specific clinical presentations of RBF, particularly in dengue-endemic areas, and that molecular diagnostic techniques may aid in correct identification and management.

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Publication Details

Journal
ASM Case Reports
Published
2025-05-08
DOI
https://doi.org/10.1128/asmcr.00108-24
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
0.00
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article

False-positive dengue IgM in Streptobacillus moniliformis rat-bite fever: the need to look beyond the rapid test—a case report

Jun Yang Tay, Srishti Chhabra, Yan Tan, Yihui Chen
ASM Case Reports
Mosquito-borne diseases and control
article

False-positive dengue IgM in Streptobacillus moniliformis rat-bite fever: the need to look beyond the rapid test—a case report

Jun Yang Tay, Srishti Chhabra, Yan Tan, Yihui Chen
article en

Abstract

This case highlights the diagnostic challenge posed by cross-reactive dengue serology in RBF, emphasizing the need to avoid relying solely on IgM positivity for diagnosing dengue fever. Although comparatively less common, clinicians should be aware of non-specific clinical presentations of RBF, particularly in dengue-endemic areas, and that molecular diagnostic techniques may aid in correct identification and management.

ASM Case ReportsVol. 1(4)
Tan Tock Seng Hospital (SG), National University Hospital (SG)
Good health and well-being
Openalex Percentile: Top 86%
Mosquito-borne diseases and control
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