ZAR1 and ZAR2 orchestrate the dynamics of maternal mRNA polyadenylation during mouse oocyte development
The jointly analyzed multi-omics data highlight the limitations of Smart-seq2 in oocytes, clarify the dynamics of the maternal transcriptome, and uncover new roles of ZAR1 in regulating the maternal transcriptome.
Authors
- Ruibao Su (ORCID: https://orcid.org/0000-0002-7548-894X)
- Heng‐Yu Fan (ORCID: https://orcid.org/0000-0003-4544-4724)
- Zhiyan Jiang (ORCID: https://orcid.org/0000-0002-0372-8422)
- Rong Yan (ORCID: https://orcid.org/0000-0001-7925-1280)
- Yu-Ke Wu
- Falong Lu (ORCID: https://orcid.org/0000-0002-8321-4818)
- Yun‐Wen Wu
- Yuanchao Xue (ORCID: https://orcid.org/0000-0002-8113-2333)
- Shu‐Yan Ji
- Jingwen Liu (ORCID: https://orcid.org/0000-0002-0748-7830)
- Zhiyi Li (ORCID: https://orcid.org/0009-0008-0779-9720)
- Zhuoyue Niu
Institutions
- Chinese Academy of Sciences (CN)
- Columbus State University (US)
- Sir Run Run Shaw Hospital (CN)
- Institute of Biophysics (CN)
- Institute of Genetics and Developmental Biology (CN)
- University of Chinese Academy of Sciences (CN)
- The Ohio State University (US)
- Zhejiang University (CN)
Publication Details
- Journal
- Genome biology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1186/s13059-025-03593-8
- Citations
- 2
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China
- Natural Science Foundation of Zhejiang Province