Simultaneous determination of cefmetazole and cefaclor in urine from pediatric patients with urinary tract infections using a newly developed high-performance liquid chromatography assay method
We developed and validated an HPLC-UV method for the simultaneous measurement of cefaclor and cefmetazole in pediatric patients with UTI. The assay is rapid, cost-effective, and suitable for therapeutic drug monitoring.
Authors
- E.E. Maeda
- Ryo Karato
- Yoshifusa Abe (ORCID: https://orcid.org/0000-0002-4861-8200)
- Kenji Momo (ORCID: https://orcid.org/0000-0001-9856-0097)
- Kurumi Abe (ORCID: https://orcid.org/0000-0001-5830-5673)
- Hitomi Sawai (ORCID: https://orcid.org/0000-0002-0714-8337)
- Takeru Kanazawa (ORCID: https://orcid.org/0000-0002-6794-1847)
- Izumi Takayama
Publication Details
- Journal
- International Journal of Clinical Pharmacology and Therapeutics
- Published
- 2025-05-08
- DOI
- https://doi.org/10.5414/cp204741
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00