Massive Thymic Hyperplasia in Graves Disease

Thymic hyperplasia (TH) is a rare but established complication of Graves disease (GD). It is a benign phenomenon that regresses with appropriate treatment of GD. We report the case of a Burmese refugee with newly diagnosed GD, who had an incidental thymic mass measuring 70 mm × 21 mm × 121 mm. The size of the mass exceeded typical reports in the literature but was not accompanied by a substantial thyrotoxicosis. As the mass receded with antithyroid medication, a presumptive diagnosis of TH was ultimately made. Recognition of this association is vital to prevent unnecessary biopsy and surgical intervention.

Authors

Institutions

Publication Details

Journal
JCEM Case Reports
Published
2025-04-18
DOI
https://doi.org/10.1210/jcemcr/luaf076
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Massive Thymic Hyperplasia in Graves Disease

D Luong, Simon Ryder, Gaurav Puri, Christopher Chun-lin Chan
JCEM Case Reports
Myasthenia Gravis and Thymoma
article

Massive Thymic Hyperplasia in Graves Disease

D Luong, Simon Ryder, Gaurav Puri, Christopher Chun-lin Chan
article en

Abstract

Thymic hyperplasia (TH) is a rare but established complication of Graves disease (GD). It is a benign phenomenon that regresses with appropriate treatment of GD. We report the case of a Burmese refugee with newly diagnosed GD, who had an incidental thymic mass measuring 70 mm × 21 mm × 121 mm. The size of the mass exceeded typical reports in the literature but was not accompanied by a substantial thyrotoxicosis. As the mass receded with antithyroid medication, a presumptive diagnosis of TH was ultimately made. Recognition of this association is vital to prevent unnecessary biopsy and surgical intervention.

JCEM Case ReportsVol. 3(6)
Griffith University (AU), Queensland Health (AU), The University of Queensland (AU), Logan Hospital (AU), Metro South Health (AU)
Good health and well-being
Openalex Percentile: Top 84%
Myasthenia Gravis and Thymoma
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Massive Thymic Hyperplasia in Graves Disease — D Luong, Simon Ryder, et al. · JCEM Case Reports (2025) | TGRS Research Map | TGRS