Early-life and concurrent predictors of the healthy adolescent microbiome in a cohort study
Our study suggests that adolescence is a unique window for gut microbial composition and that it may be shaped by both early-life and concurrent exposures, highlighting its potential in future epidemiologic research.
Authors
- Amy D. Willis (ORCID: https://orcid.org/0000-0002-2802-4317)
- Kim M. Cecil (ORCID: https://orcid.org/0000-0001-8233-5485)
- Abby F. Fleisch (ORCID: https://orcid.org/0000-0002-2789-6412)
- Hannah E. Laue (ORCID: https://orcid.org/0000-0002-2578-103X)
- Juliette C. Madan
- Kimberly Yolton (ORCID: https://orcid.org/0000-0002-4458-0516)
- Melinda C. MacDougall (ORCID: https://orcid.org/0009-0005-5821-3097)
- Margaret Rita Karagas (ORCID: https://orcid.org/0000-0002-6398-7362)
- Jessie Poulin Buckley (ORCID: https://orcid.org/0000-0001-7976-0157)
- Bruce P. Lanphear (ORCID: https://orcid.org/0000-0003-2598-5574)
- Fang Wang (ORCID: https://orcid.org/0000-0002-0862-696X)
- Aimin Chen (ORCID: https://orcid.org/0000-0001-9713-6438)
- Joseph M. Braun (ORCID: https://orcid.org/0000-0002-5239-3235)
- Yingying Xu (ORCID: https://orcid.org/0000-0001-5247-3721)
Institutions
- Dartmouth College (US)
- University of North Carolina at Chapel Hill (US)
- Dartmouth–Hitchcock Medical Center (US)
- Maine Medical Center (US)
- Simon Fraser University (CA)
- University of Washington (US)
- Brown University (US)
- Cincinnati Health Department (US)
- MaineHealth (US)
- Dartmouth Psychiatric Research Center (US)
- Maine Medical Center (US)
- University of Cincinnati (US)
- Columbia University (US)
- University of Pennsylvania (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Genome Medicine
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1186/s13073-025-01481-1
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Institute of General Medical Sciences
- National Center for Advancing Translational Sciences