Hormonal regulation of neurogenesis

The key process for studying neuroplasticity is neurogenesis and the participation of hormones in it. The purpose of this review is to analyze the latest data obtained by researchers in this field and to form a general understanding of the molecular mechanisms of the action of hormones on the stages of neurogenesis. The literature was studied, including scientific domestic and foreign publications that were prepared mainly over the past five years. The research methods were the analysis of primary sources and scientific results obtained by other authors. The use of comparative analysis made it possible to study and compare the types of action of hormones depending on the place of their synthesis. The use of the systemic-structural method made it possible to formulate the author’s diagram reflecting the influence of hormones on neurogenesis. The review examines the influence of hormones on neurogenesis. It has been established that a decrease in the concentration of hormones or disruption of their metabolism can cause the development of pathological conditions. The similarities between neural and vascular networks in the mechanisms of their growth and development have been revealed. The conclusion is formulated about the need to study the mechanisms of the relationship between neurogenesis and angiogenesis in order to identify new molecules that regulate the activity of proneurogenic or proangiogenic cells.