Time to Reappraise the Antibiotic Treatment for Methicillin-Susceptible <i>Staphylococcus aureus</i> Infective Endocarditis: Data From the Experimental Model

In the MSSA experimental endocarditis model, daptomycin combinations with β-lactams had significantly better activity than any of the monotherapies in sterilizing valve vegetations and preventing DNS development. These findings support their use in clinical practice and to perform clinical trials.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2025-05-08
DOI
https://doi.org/10.1093/infdis/jiaf245
Citations
2
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
Field-Weighted Citation Impact
2.79
Controls
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article

Time to Reappraise the Antibiotic Treatment for Methicillin-Susceptible Staphylococcus aureus Infective Endocarditis: Data From the Experimental Model

Guillermo Cuervo, Oriol Ferret Gasch, Bárbara Vidal, Andrés Perissinotti et al.
2 citations
The Journal of Infectious Diseases
Antimicrobial Resistance in Staphylococcus
2.79
article

Time to Reappraise the Antibiotic Treatment for Methicillin-Susceptible Staphylococcus aureus Infective Endocarditis: Data From the Experimental Model

Guillermo Cuervo, Oriol Ferret Gasch, Bárbara Vidal, Andrés Perissinotti, María Alexandra Cañas, Juan Ambrosioni, Asunción Moreno, Eduard Quintana, Carlos Falces, Juan M. Pericàs, Francesc Marco, J. García-González, Jaume Llopis, José M. Miró, C. García-de-la-Mària, José M Tolosana, Marta Hernández-Meneses
article en
2 citations

Abstract

In the MSSA experimental endocarditis model, daptomycin combinations with β-lactams had significantly better activity than any of the monotherapies in sterilizing valve vegetations and preventing DNS development. These findings support their use in clinical practice and to perform clinical trials.

The Journal of Infectious DiseasesVol. 232(3)
Universitat Autònoma de Barcelona (ES), Instituto de Salud Carlos III (ES), Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES), Hospital Clínic de Barcelona (ES), Corporació Sanitària Parc Taulí (ES), Institute of Research and Innovation Parc Tauli (ES), Barcelona Institute for Global Health (ES), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES), Universitat de Barcelona (ES)
Life in Land
Openalex Percentile: Top 11%
Antimicrobial Resistance in Staphylococcus
2.79
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