Clinical neuropathology of early‐stage Pick's disease initially diagnosed as depressive disorder: A case report and case series comparison
The clinical symptoms in this case, primarily characterized by apathy with minimal behavioral symptoms, were consistent with the predominant pathological involvement of the dorsolateral frontal lobe. The present case was interpreted as early-phase PiD. A comparison of the case series suggested that early-phase PiD cases may help clarify the association between early clinical manifestations and focal degenerative lesions in the frontal lobe.
Authors
- Araki Kimura
- Ito Kawakami (ORCID: https://orcid.org/0000-0003-1989-2398)
- Kazuhiro Niizato
- Masato Hasegawa (ORCID: https://orcid.org/0000-0001-7415-8159)
- Tadafumi Kato (ORCID: https://orcid.org/0000-0001-7856-3952)
- Kenichi Oshima
- Kenji Ikeda (ORCID: https://orcid.org/0000-0003-1380-4983)
- Akito Nagakura
Institutions
- Tokyo Metropolitan Matsuzawa Hospital (JP)
- Juntendo University (JP)
- Tokyo Metropolitan Institute of Medical Science (JP)
Publication Details
- Journal
- Psychiatry and Clinical Neurosciences Reports
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1002/pcn5.70116
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Japan Agency for Medical Research and Development