The role of triglycerides in predicting new-onset arthritis in the general population over 45 years old: evidence from the China health and retirement longitudinal study

Elevated TG levels were significantly associated with an increased risk of arthritis, and this association was partially mediated by HDL-C. The findings suggest that interventions targeting reduced TG levels and enhanced HDL function may have potential value in arthritis prevention. Future studies should focus on lipid metabolism intervention strategies to reduce arthritis risk and delay disease progression, providing a new scientific basis for arthritis management.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-05-08
DOI
https://doi.org/10.3389/fendo.2025.1530874
Citations
1
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
Field-Weighted Citation Impact
1.67
Controls
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article

The role of triglycerides in predicting new-onset arthritis in the general population over 45 years old: evidence from the China health and retirement longitudinal study

Huanan Li, W. F. Mader, Qipeng Yuan, Honggu Chen et al.
1 citations
Frontiers in Endocrinology
Rheumatoid Arthritis Research and Therapies
1.67
article

The role of triglycerides in predicting new-onset arthritis in the general population over 45 years old: evidence from the China health and retirement longitudinal study

Huanan Li, W. F. Mader, Qipeng Yuan, Honggu Chen, Jing Deng
article en
1 citations

Abstract

Elevated TG levels were significantly associated with an increased risk of arthritis, and this association was partially mediated by HDL-C. The findings suggest that interventions targeting reduced TG levels and enhanced HDL function may have potential value in arthritis prevention. Future studies should focus on lipid metabolism intervention strategies to reduce arthritis risk and delay disease progression, providing a new scientific basis for arthritis management.

Frontiers in EndocrinologyVol. 16
Jiangxi University of Traditional Chinese Medicine (CN), Guangxi University (CN), Wenzhou Medical University (CN), Guangxi University of Chinese Medicine (CN), Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine (CN), Zhejiang Taizhou Hospital (CN)
Good health and well-being
Openalex Percentile: Top 18%
Rheumatoid Arthritis Research and Therapies
1.67
DOIOpen Access PDFOpenAlex
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