Prediction of new candidate proteins and analysis of sub-modules and protein hubs associated with seed development in rice (Oryza sativa) using an ensemble network-based systems biology approach

These findings, including the identified hub proteins and sub-modules, provide a better understanding of the PPI interaction landscape governing seed development in rice. This information is useful for achieving a systems biology understanding of seed development. This study implements an ensemble of algorithms for the analysis and showcases how systems biology techniques can be applied in developmental biology.