High expression of CXCL13 predicts a favorable response to immunotherapy by upregulating CXCR5+CD8+ T-cell infiltration in gastric cancer
This study identified CXCL13 as a prognostic factor in GC patients receiving ICI therapy, emphasizing its critical role in the antitumor microenvironment via CXCR5+CD8+ T cells.
Authors
- Hua Bai (ORCID: https://orcid.org/0000-0003-0849-524X)
- Ying Liu (ORCID: https://orcid.org/0000-0001-5718-7804)
- Ting Deng (ORCID: https://orcid.org/0000-0001-5477-7972)
- Yansha Sun
- Ning Tao (ORCID: https://orcid.org/0000-0001-6027-5039)
- Yao Lu
- Shuning Xu
- Lei Qiao
- Danyang Li (ORCID: https://orcid.org/0000-0002-4795-5766)
Institutions
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Zhengzhou University (CN)
- Henan Cancer Hospital (CN)
- Zhengzhou People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1551259
- Citations
- 5
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 5.23