Fatal risk factors and the efficacy of glucocorticoid therapy in severe fever with thrombocytopenia syndrome: a multicenter retrospective cohort study
A new nomogram based on five independent risk factors effectively predicts the prognosis of SFTS. Severe patients and those with low AST levels might benefit from GCs therapy while early and relatively high doses of GCs therapy should be used with caution.
Authors
- Shuting Liu (ORCID: https://orcid.org/0009-0004-8972-7739)
- Fang Zhong (ORCID: https://orcid.org/0000-0002-3165-6884)
- Jin Tian (ORCID: https://orcid.org/0000-0002-5202-7796)
- Chengxi Zheng
- Zhiliang Hu (ORCID: https://orcid.org/0000-0001-8543-821X)
- Zhihang Peng (ORCID: https://orcid.org/0000-0003-4372-2487)
- Xin Zheng (ORCID: https://orcid.org/0000-0001-9176-8856)
- Shiyu Zhang (ORCID: https://orcid.org/0009-0009-7047-1872)
- Bin Zhu (ORCID: https://orcid.org/0000-0003-1802-4951)
- Hongming Huang
- Baoju Wang (ORCID: https://orcid.org/0000-0002-8363-1224)
- Qinyu You
- Dilihumaer Zhayier
Institutions
- Nanjing University of Chinese Medicine (CN)
- Union Hospital (HK)
- Chinese Center For Disease Control and Prevention (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Huazhong University of Science and Technology (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.3389/fcimb.2025.1531880
- Citations
- 3
- Primary Topic
- Viral Infections and Vectors
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China